Paraneoplastic Sarcoidosis in Multiple Myeloma

Double pathology, sarcoidosis associated with multiple myeloma: A case report

The association of sarcoidosis with multiple myeloma is not well known. Including this case report, 12 cases of patients with both sarcoidosis and multiple myeloma have been reported in the literature. The skeletal lesions of both conditions have many clinical and radiological similarities, and unless clinicians are aware of the association and the possibility of dual pathologies, the diagnosis...

Sarcoidosis and multiple myeloma: an association.

An association between sarcoidosis and neoplasia has been suggested. The development of malignant lymphoma has been reported in several patients with sarcoidosis,2 but there have been few reports of patients with sarcoidosis and multiple myeloma.24 We describe five patients with sarcoidosis who developed multiple myeloma. Case histories The table shows details offive patients with sarcoidosis s...

Studies in serum electrolytes; the calcium-binding property of the serum proteins (multiple myeloma, lymphogranuloma venereum and sarcoidosis.

Paraneoplastic Addisonian pigmentation and acquired ichthyosis as presenting features of multiple myeloma.

Black brown hyperpigmentation of the mucosae, sunexposed skin, palmar creases and frictional sites (Addisonian pigmentation) is characteristic of Addison disease. However, it can also occur as a paraneoplastic manifestation of tumours like bronchogenic carcinoma. Acquired ichthyosis starts later in life and can also be a paraneoplastic presentation. We report a unique combination of paraneoplas...

The Effect of Prednisone on Calcium Metabolism and Ca47 Kinetics in Patients with Multiple Myeloma and Hypercalcemia.

Hypercalcemia is a frequent complication of multiple myeloma and has been observed in 43% of the 76 patients admitted to the Clinical Center of the National Institutes of Health from 1953 to 1961 (2). The pathogenesis of the hypercalcemia associated with multiple myeloma has been attributed to excessive bone resorption (3). Carbohydrate-active steroids have been successfully used to correct hyp...